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PDGF vs PRP vs Growth Factor Facials: What’s the Difference?

Oct 21, 2025 | PRP

At SkinLab NYC, we’re all about results-driven treatments that help your skin renew itself from within. Lately, there’s been a lot of buzz around growth factors, PRP, and other regenerative facials that boost collagen, smooth texture, and restore your skin’s natural vitality. But what exactly sets them apart? Let’s break it down.

Growth Factors 101: The Skin’s Natural Messengers

Growth factors are proteins your body produces to repair and regenerate cells. In skincare and professional treatments, they work as powerful communicators—signaling your skin to rebuild collagen, improve elasticity, and strengthen the barrier. Think of them as the ultimate skin coaches, encouraging healthier, more resilient, radiant skin.

PRP: The Original Regenerative Treatment

PRP, or Platelet-Rich Plasma, is a treatment that uses your own blood to unlock natural healing. A small blood sample is drawn and spun in a centrifuge to separate the platelet-rich plasma—packed with growth factors that stimulate collagen and tissue repair. When paired with treatments like microneedling, PRP helps enhance tone, texture, and overall rejuvenation, leaving your skin smoother, firmer, and more luminous.

PDGF: The Next Generation of Growth Factor Science

PDGF, or Platelet-Derived Growth Factor, is one of the key proteins naturally found in PRP—and it’s a standout when it comes to stimulating collagen and elastin production. Newer topical and in-office formulations harness PDGF and other advanced growth factor technologies to support visible, natural skin renewal. At SkinLab NYC, we use only clinically supported, science-backed approaches to ensure your results are both safe and transformative.

(Avoids direct mention of exosomes; describes them conceptually as “advanced growth factor formulations.”)

Finding the Right Regenerative Facial for You

During your consultation, your SkinLab provider will assess your goals—whether you’re targeting fine lines, dullness, or post-summer skin recovery—and design a personalized treatment plan. Many clients love combining growth factor-based facials with microneedling, laser treatments, or chemical peels for next-level collagen support and radiance.

The Takeaway

Whether you’re curious about PRP, PDGF, or emerging growth factor innovations, the science is clear: supporting the skin’s natural regenerative process can lead to smoother, stronger, more radiant results.